SCHEMBL17879684

SCHEMBL17879684

O=C(O)CN(CC(=O)OCc1ccccc1)S(=O)(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.56
MAPK1 P28482 2/20 0.53
CA1 P00915 8/20 0.52
CA2 P00918 8/20 0.52
CA4 P22748 2/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
MMP14 P50281 1/20 0.49
MMP16 P51512 1/20 0.49
ALDH1A1 P00352 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
DAGLA Q9Y4D2 2/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5295487 0.79 TAS2R14 (0.64) KEAP1MAPK1ALDH1A1DAGLA
SCHEMBL17879690 0.78 CA1 (0.44) KEAP1MAPK1CA1CA2CA4
SCHEMBL17879683 0.77 CA1 (0.66) MAPK1CA1CA2CA4ALDH1A1
SCHEMBL17879693 0.77 CA1 (0.66) MAPK1CA1CA2CA4ALDH1A1
SCHEMBL11802279 0.76 MAPK1 (0.71) KEAP1MAPK1MMP1MMP2MMP9
SCHEMBL13589983 0.74 CA1 (0.68) MAPK1CA1CA2CA4ALDH1A1
SCHEMBL18283191 0.74 ALDH1A1 (0.56) MAPK1CA1CA2CA4ALDH1A1
SCHEMBL3093075 0.74 CA1 (0.68) MAPK1CA1CA2CA4ALDH1A1
SCHEMBL5285705 0.73 MAPK1 (0.63) KEAP1MAPK1MMP1MMP2MMP9
SCHEMBL1133911 0.73 MMP2 (0.82) KEAP1MAPK1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10001584-B2 Optical film, and polarizing plate and liquid crystal display device that use this optical film FUJIFILM CORPORATION (JP) 2018-06-19 US disclosed
US-10001584-B2 Optical film, and polarizing plate and liquid crystal display device that use this optical film FUJIFILM CORPORATION (JP) 2018-06-19 US disclosed
US-20160187537-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE THAT USE THIS OPTICAL FILM FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed
US-20160187537-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE THAT USE THIS OPTICAL FILM FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed