SCHEMBL17879690

SCHEMBL17879690

CCCCS(=O)(=O)N(CC(=O)O)CC(=O)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.44
CA2 P00918 8/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPK1 P28482 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 1/20 0.43
CA4 P22748 2/20 0.42
KEAP1 Q14145 1/20 0.40
BMP1 P13497 1/20 0.40
AR P10275 1/20 0.40
CETP P11597 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19532138 0.79 MMP2 (0.50) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879684 0.78 KEAP1 (0.56) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879689 0.75 L3MBTL1 (0.57) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL24127602 0.73 LTA4H (0.55) ALDH1A1MAPK1L3MBTL1CYP3A4TSHR
SCHEMBL23350078 0.73 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1CYP3A4TSHR
SCHEMBL18283191 0.72 ALDH1A1 (0.56) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879683 0.72 CA1 (0.66) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL133636 0.72 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1CYP3A4TSHR
SCHEMBL12711081 0.72 CNR2 (0.55) CA2ALDH1A1L3MBTL1TDP1
SCHEMBL17879693 0.72 CA1 (0.66) CA1CA2ALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10001584-B2 Optical film, and polarizing plate and liquid crystal display device that use this optical film FUJIFILM CORPORATION (JP) 2018-06-19 US disclosed
US-10001584-B2 Optical film, and polarizing plate and liquid crystal display device that use this optical film FUJIFILM CORPORATION (JP) 2018-06-19 US disclosed
US-20160187537-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE THAT USE THIS OPTICAL FILM FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed
US-20160187537-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE THAT USE THIS OPTICAL FILM FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed