SCHEMBL1788265

SCHEMBL1788265

CCC(CC(=O)O)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
FFAR3 O14843 1/20 0.32
GPR84 Q9NQS5 4/20 0.31
FFAR1 O14842 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP12 P39900 1/20 0.30
MMP14 P50281 1/20 0.30
MMP15 P51511 1/20 0.30
MMP16 P51512 1/20 0.30
MMP26 Q9NRE1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790252 0.88 THRB (0.31) SLC22A6ALDH1A1TDP1
SCHEMBL1604218 0.82 SLC22A6 (0.36) SLC22A6TDP1FFAR3GPR84SMN1; SMN2
SCHEMBL8877041 0.75 SLC22A6 (0.31) SLC22A6TDP1
SCHEMBL14261124 0.75 SLC22A6 (0.38) SLC22A6TDP1FFAR3GPR84SMN1; SMN2
SCHEMBL15555383 0.75 SLC22A6 (0.38) SLC22A6TDP1FFAR3GPR84SMN1; SMN2
SCHEMBL26984814 0.73 HMGCR (0.39) SLC22A6ALDH1A1TDP1FFAR3GPR84
SCHEMBL8877183 0.71 SLC22A6 (0.43) SLC22A6TDP1SMN1; SMN2MAPT
SCHEMBL1704335 0.70 SLC22A6 (0.38) SLC22A6TDP1GPR84SMN1; SMN2
SCHEMBL16877270 0.70 SLC22A6 (0.43) SLC22A6TDP1GPR84SMN1; SMN2MAPT
SCHEMBL499817 0.70 GPR84 (0.39) SLC22A6ALDH1A1TDP1FFAR3GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123925-A1 POLYMER FOR PROTECTIVE LAYER OF RESIST, AND POLYMER COMPOSITION INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-05-26 US disclosed