Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545066 | 1.00 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL10976798 | 1.00 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12608306 | 0.97 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL17392756 | 0.97 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1788508 | 0.97 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL23512039 | 0.92 | CYP3A4 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1841223 | 0.92 | — | — | |
| SCHEMBL9529889 | 0.88 | ALDH1A1 (0.31) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL19344722 | 0.87 | BLM (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11995937 | 0.86 | MEN1 (0.42) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090651-B2 | Helix 12 directed pharmaceutical products | ENDORECHERCHE, INC. (CA) | 2015-07-28 | — | — | US | disclosed |
| CN-102358750-A | Helix 12 directed pharmaceutical products | ENDORECH INC | 2012-02-22 | — | — | CN | disclosed |
| US-20090082378-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
| CN-1930181-A | Helix 12 directed steroidal drugs | ENDORECH INC (CA) | 2007-03-14 | — | — | CN | disclosed |
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | ENDORECHERCHE, INC. | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250749-A1 | Helix 12 directed pharmaceutical products | SHBG, AR, NR5A1 | MEN1 2170/4885THRB 742/4885HTT 367/4885 |
| US-20090082378-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE B2 ADRENERGIC RECEPTOR | ADRB2, ADRA2C, ADRB1 | MEN1 4112/4885THRB 77/4885HTT 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.