Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405782 | 0.85 | POLB (0.59) | POLBMAPK1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL17888980 | 0.83 | POLB (0.50) | POLBMAPK1ALOX15ALDH1A1LMNA | |
| SCHEMBL403762 | 0.82 | ALDH1A1 (0.55) | POLBMAPK1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL17888978 | 0.81 | MMP13 (0.58) | USP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10054290 | 0.80 | MAPK1 (0.48) | POLBMAPK1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL398946 | 0.80 | POLB (0.52) | POLBMAPK1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL17888982 | 0.79 | MAPT (0.49) | POLBLMNASMN1; SMN2TDP1KDM4E | |
| SCHEMBL17888981 | 0.77 | KDM4E (0.65) | POLBMAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL404827 | 0.76 | PDE5A (0.58) | POLBMAPK1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL17888979 | 0.76 | ALDH1A1 (0.50) | POLBALDH1A1KDM4EMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050739-B1 | QUINAZOLINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2016-07-06 | — | — | EP | claimed |