Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17889672 | 1.00 | SIRT5 (0.64) | SIRT5FOLH1CTSLCTSSCPB1 | |
| SCHEMBL16782306 | 0.92 | SIRT2 (0.66) | SIRT5FOLH1CPB1CPB2SIRT2 | |
| SCHEMBL12085048 | 0.91 | MAPT (0.63) | SIRT5FOLH1CTSLCTSSCPB1 | |
| SCHEMBL27138126 | 0.88 | KMT2A (0.57) | SIRT5FOLH1CPB1CPB2 | |
| SCHEMBL27138128 | 0.88 | KMT2A (0.57) | SIRT5FOLH1CPB1CPB2 | |
| SCHEMBL5406791 | 0.88 | CPB1 (0.62) | SIRT5FOLH1CTSLCTSSCPB1 | |
| SCHEMBL9516479 | 0.88 | SIRT2 (0.62) | SIRT5CTSLCTSSCPB1CPB2 | |
| SCHEMBL14519212 | 0.88 | CPB1 (0.62) | SIRT5FOLH1CTSLCTSSCPB1 | |
| SCHEMBL23574915 | 0.88 | PTGER4 (0.70) | SIRT5FOLH1SIRT2SIRT1SIRT3 | |
| SCHEMBL22750161 | 0.88 | PTGER4 (0.70) | SIRT5FOLH1SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021256546-A1 | METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS | 味の素株式会社 | 2021-12-23 | — | — | WO | disclosed |
| US-20190117745-A1 | DRUG DELIVERY METHOD | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-04-25 | — | — | US | disclosed |
| US-10117912-B2 | Drug delivery method | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-06 | — | — | US | disclosed |
| US-20160193305-A1 | DRUG DELIVERY METHOD | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117745-A1 | DRUG DELIVERY METHOD | SI, TMPRSS2, TMPRSS15 | SIRT5 1733/4885FOLH1 639/4885CTSL 605/4885 |
| US-10117912-B2 | Drug delivery method | SI, TMPRSS2, TMPRSS15 | SIRT5 1733/4885FOLH1 639/4885CTSL 605/4885 |
| US-20160193305-A1 | DRUG DELIVERY METHOD | SI, TMPRSS2, TMPRSS15 | SIRT5 1733/4885FOLH1 639/4885CTSL 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.