SCHEMBL17891122

SCHEMBL17891122

CC1(C)OC(C)(C)C(O)=C(c2c(C3CC3)ccc(-c3ccc(Cl)cc3)c2F)C1=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31
FPR1 P21462 1/20 0.30
FPR2 P25090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25440018 0.90 CNR1 (0.31) ACACBACACA
SCHEMBL28337831 0.84 SLC6A3 (0.38) ALOX5APFEN1
SCHEMBL28340174 0.84 ALOX5AP (0.31) ALOX5APFEN1
SCHEMBL17891208 0.83 USP7 (0.33)
SCHEMBL12129299 0.81 PDE3B (0.35) ALOX5AP
SCHEMBL13574111 0.81 PDE3B (0.35)
SCHEMBL12128952 0.81 ACACB (0.38) ACACBACACA
SCHEMBL29538786 0.80 FASN (0.35) ACACBACACAFPR1FPR2
SCHEMBL10121135 0.80 FASN (0.35) ACACBACACAFPR1FPR2
SCHEMBL29435275 0.77 EDNRB (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766044-B2 Method for controlling PPO resistant weeds BASF SE (DE) 2023-09-26 US disclosed
US-20220361495-A1 METHOD FOR CONTROLLING PPO RESISTANT WEEDS BASF SE (DE) 2022-11-17 US disclosed
US-10968462-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2021-04-06 US disclosed
US-20170029383-A1 Diaminotriazine Derivatives as Herbicides BASF SE (DE) 2017-02-02 US disclosed
US-20160194654-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF Agro B.V. (NL) 2016-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170029383-A1 Diaminotriazine Derivatives as Herbicides DDT, CBR3, HDHD5 ALOX5AP 2141/4885FEN1 4656/4885ACACB 2317/4885
US-10968462-B2 Plants having increased tolerance to herbicides PPOX, PNPO, PIN1 ALOX5AP 1593/4885FEN1 298/4885ACACB 1720/4885
US-20220361495-A1 METHOD FOR CONTROLLING PPO RESISTANT WEEDS PPOX, PNPO, NOTUM ALOX5AP 365/4885FEN1 3720/4885ACACB 565/4885
US-11766044-B2 Method for controlling PPO resistant weeds PPOX, PNPO, NOTUM ALOX5AP 365/4885FEN1 3720/4885ACACB 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.