Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891299 | 0.92 | MMP12 (0.50) | MMP12ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL29061553 | 0.90 | MMP12 (0.48) | MMP12ALDH1A1TSHRSMN1; SMN2CTSK | |
| SCHEMBL13572273 | 0.88 | CTSK (0.52) | TSHRCTSKALPIPKMPTGS1 | |
| SCHEMBL29023304 | 0.87 | MMP12 (0.46) | MMP12ALDH1A1TSHRSMN1; SMN2CTSK | |
| SCHEMBL15949718 | 0.85 | TSHR (0.46) | MMP12ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL28199415 | 0.85 | CTSK (0.51) | ALDH1A1TSHRCTSKALPIPKM | |
| SCHEMBL3294600 | 0.83 | CTSK (0.48) | ALDH1A1CTSK | |
| SCHEMBL10632039 | 0.83 | ALDH1A1 (0.44) | MMP12ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL6545250 | 0.82 | ALDH1A1 (0.43) | MMP12ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL6950454 | 0.81 | KEAP1 (0.47) | MMP12TSHRCTSKMMEKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025022004-A2 | OPHTHALMIC LENS | CONTAMAC LIMITED (GB) | 2025-01-30 | — | — | WO | disclosed |
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | CONTAMAC LIMITED (GB) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194424-A1 | MONOMERS FOR USE IN A POLYMERIZABLE COMPOSITION AND HIGH REFRACTIVE INDEX POLYMER FOR OPTHALMIC APPLICATIONS | NR2E3, NR1I2, NR1I3 | MMP12 2834/4885ALDH1A1 267/4885TSHR 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.