Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714108 | 1.00 | LMNA (0.45) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL17901028 | 1.00 | LMNA (0.45) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL25325632 | 0.82 | LMNA (0.48) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL1495894 | 0.82 | LMNA (0.48) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL25882988 | 0.81 | CA4 (0.43) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL941113 | 0.81 | CA4 (0.43) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL1453272 | 0.81 | CA4 (0.48) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL11210416 | 0.80 | LMNA (0.47) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL1252991 | 0.78 | LMNA (0.45) | LMNAMTNR1AMTNR1BGAACYP1A2 | |
| SCHEMBL23269716 | 0.77 | KDM4E (0.44) | LMNAMTNR1AMTNR1BGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205398-B | Pyridine amide compounds having fungicidal activity | 美国陶氏益农公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180000084-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2018-01-04 | — | — | US | disclosed |
| US-20170360038-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-12-21 | — | — | US | disclosed |
| US-20170360038-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-12-21 | — | — | US | disclosed |
| EP-3240420-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240419-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109303-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109303-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109302-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109302-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360038-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | LMNA 3069/4885MTNR1A 2292/4885MTNR1B 2457/4885 |
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | LMNA 3069/4885MTNR1A 2292/4885MTNR1B 2457/4885 |
| US-20180000084-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CYP1A2, CYP51A1 | LMNA 3114/4885MTNR1A 1890/4885MTNR1B 2054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.