SCHEMBL1789406

SCHEMBL1789406

C=C(CCC=Cc1cccc([N+](=O)[O-])c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.55
MAPT P10636 5/20 0.52
MAOB P27338 1/20 0.52
FBP1 P09467 1/20 0.50
VCP P55072 1/20 0.50
CYP19A1 P11511 1/20 0.50
ALDH1A1 P00352 5/20 0.49
CYP1A2 P05177 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
HTT P42858 2/20 0.47
GAA P10253 1/20 0.46
GLO1 Q04760 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HSP90AA1 P07900 2/20 0.45
MITF O75030 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14423634 0.87 NFE2L2 (0.60) NFE2L2MAPTMAOBFBP1VCP
SCHEMBL1791768 0.84 GRIK1 (0.48) MAPTMAOBFBP1MEN1KMT2A
SCHEMBL2923817 0.79 NFE2L2 (0.61) NFE2L2MAPTMAOBFBP1VCP
SCHEMBL7560311 0.79 NFE2L2 (0.61) NFE2L2MAPTMAOBFBP1VCP
SCHEMBL4632192 0.79 NFE2L2 (0.65) NFE2L2MAPTMAOBFBP1VCP
SCHEMBL4632191 0.79 NFE2L2 (0.65) NFE2L2MAPTMAOBFBP1VCP
SCHEMBL8115998 0.79 PAM (0.52) MAPTMAOBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL699686 0.79 PAM (0.52) MAPTMAOBALDH1A1CYP1A2SMN1; SMN2
SCHEMBL1787322 0.79 CYP1A2 (0.50) MAOBFBP1ALDH1A1CYP1A2MEN1
SCHEMBL18041433 0.78 NFE2L2 (0.56) NFE2L2MAPTMAOBFBP1VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS NFE2L2 405/4885MAPT 3766/4885MAOB 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.