Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17894475 | 0.90 | GID4 (0.61) | MAOBGID4RXRARXRBRXRG | |
| SCHEMBL17894461 | 0.90 | NPC1 (0.55) | MAOBGID4MAOANPC1RAB9A | |
| SCHEMBL17894482 | 0.85 | MAOB (0.57) | MAOBMAOANPC1RAB9AF2 | |
| SCHEMBL17894442 | 0.84 | MAOB (0.48) | MAOBGID4MAOAF2CYP2D6 | |
| SCHEMBL17894552 | 0.83 | BCHE (0.63) | MAOBMAOARAB9ASMN1; SMN2F2 | |
| SCHEMBL8935243 | 0.83 | GID4 (0.74) | MAOBGID4RXRARXRBRXRG | |
| SCHEMBL13134026 | 0.83 | HTR3E (0.61) | NPC1RAB9AALOX12 | |
| SCHEMBL17894553 | 0.83 | MAOB (0.61) | MAOBRXRARXRBRXRGMAOA | |
| Hydrochloric Acid SCHEMBL8935260 | 0.82 | GID4 (0.73) | MAOBGID4RXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL8202366 | 0.82 | MRGPRX1 (0.61) | MAOBF2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | claimed |
| EP-3240775-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | Swansea University (GB) | 2017-11-08 | — | — | EP | claimed |
| WO-2016108045-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | SWANSEA UNIVERSITY (GB) | 2016-07-07 | — | — | WO | claimed |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | MAOB 56/4885GID4 3349/4885RXRA 2537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.