Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8935260 | 0.99 | GID4 (0.73) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL8935322 | 0.93 | GID4 (0.71) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL8935439 | 0.84 | GID4 (0.61) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL8935238 | 0.84 | LTA4H (0.67) | GID4MAOBALDH1A1KMT2A | |
| SCHEMBL17894476 | 0.83 | MAOB (0.63) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL8935332 | 0.83 | GID4 (0.62) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL962597 | 0.81 | GID4 (0.73) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL1680762 | 0.80 | MAOB (1.00) | MAOBRXRARXRBRXRGMAOA | |
| Hydrochloric Acid SCHEMBL9127887 | 0.80 | GID4 (0.71) | GID4MAOBRXRARXRBRXRG | |
| SCHEMBL29288175 | 0.80 | GID4 (0.61) | GID4MAOBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |