Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22413913 | 0.78 | PKM (0.39) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL28592282 | 0.77 | CNR1 (0.33) | PKM | |
| SCHEMBL22284505 | 0.76 | PKM (0.48) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL28626528 | 0.76 | PKM (0.48) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL22284469 | 0.75 | FBP1 (0.41) | PKMNPC1ALDH1A1RAB9AMAPT | |
| Formic Acid SCHEMBL28057288 | 0.74 | PKM (0.45) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL22284650 | 0.74 | PKM (0.39) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL29796745 | 0.73 | PKM (0.44) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL15503205 | 0.72 | PKM (0.42) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL3436871 | 0.71 | PKM (0.45) | PKMNPC1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |
| US-20220281848-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | FMC CORP (US) | 2022-09-08 | — | — | US | disclosed |
| CN-113874365-A | Pyrazole-substituted pyrrolidones as herbicides | FMC公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020242946-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | FMC CORPORATION (US) | 2020-12-03 | — | — | WO | disclosed |
| WO-2016106628-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| CN-102838546-A | Pyrazole derivatives as modulators of 5-ht2a serotonin receptor useful for treatment of disorders related thereto | ARENA PHARM INC | 2012-12-26 | — | — | CN | disclosed |
| CN-101611013-B | As 5-HT2APyrazole derivatives of serotonin receptor modulators for the treatment of disorders related thereto | ARENA PHARM INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101611013-A | As 5-HT2APyrazole derivatives of serotonin receptor modulators for the treatment of disorders related thereto | ARENA PHARM INC (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-101151251-A | Substituted pyrazolyloxyphenyl derivatives as herbicides | BAYER CROPSCIENCE AG (DE) | 2008-03-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281848-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | CBR3, PRMT9, ARG1 | PKM 1151/4885NPC1 4819/4885ALDH1A1 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.