Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957751 | 0.73 | ALDH1A1 (0.34) | PAX8 | |
| SCHEMBL28159972 | 0.71 | — | — | |
| SCHEMBL1764290 | 0.71 | — | — | |
| SCHEMBL5464777 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL1657294 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL9484445 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL5841143 | 0.70 | TP53 (0.30) | — | |
| SCHEMBL524648 | 0.68 | PAX8 (0.32) | PAX8 | |
| SCHEMBL6384699 | 0.68 | PAX8 (0.32) | PAX8 | |
| SCHEMBL702670 | 0.68 | PAX8 (0.32) | PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559731-B2 | Mutated PglB oligosaccharyl transferase enzymes | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2026-02-24 | — | — | US | disclosed |
| US-20250270520-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2025-08-28 | — | — | US | disclosed |
| EP-4389908-A2 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals S.A. (BE) | 2024-06-26 | — | — | EP | disclosed |
| EP-4010467-B1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2024-04-24 | — | — | EP | disclosed |
| EP-4291673-A2 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals SA (BE) | 2023-12-20 | — | — | EP | disclosed |
| US-20220403347-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-12-22 | — | — | US | disclosed |
| WO-2022171679-A2 | PROTEIN | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-08-18 | — | — | WO | disclosed |
| EP-4043561-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GlaxoSmithKline Biologicals SA (BE) | 2022-08-17 | — | — | EP | disclosed |
| EP-4010467-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals SA (BE) | 2022-06-15 | — | — | EP | disclosed |
| EP-3240895-B1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-01-26 | — | — | EP | disclosed |
| US-11015177-B2 | Compositions and methods for protein glycosylation | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2021-05-25 | — | — | US | disclosed |
| WO-2021028303-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2021-02-18 | — | — | WO | disclosed |
| US-20200181586-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLAXOSMITHKLINE BIOLOGICALS, SA (BE) | 2020-06-11 | — | — | US | disclosed |
| US-10577592-B2 | Compositions and methods for protein glycosylation | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2020-03-03 | — | — | US | disclosed |
| US-20190078064-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) | 2019-03-14 | — | — | US | disclosed |
| US-10150952-B2 | Compositions and methods for protein glycosylation | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2018-12-11 | — | — | US | disclosed |
| US-20180002679-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLAXOSMITHKLINE BIOLOGICALS, SA (BE) | 2018-01-04 | — | — | US | disclosed |
| EP-3240895-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GlaxoSmithKline Biologicals S.A. (BE) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016107818-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLYCOVAXYN AG (CH) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016107819-A1 | COMPOSITIONS AND METHODS FOR PROTEIN GLYCOSYLATION | GLYCOVAXYN AG (CH) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559731-B2 | Mutated PglB oligosaccharyl transferase enzymes | OSTC, PGLS, O60361 | PAX8 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.