Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564162 | 0.72 | GRIN2B (0.39) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL10961749 | 0.70 | TAAR1 (0.34) | TDP1SLC6A3 | |
| SCHEMBL3478532 | 0.64 | GBA1 (0.34) | ALDH1A1 | |
| SCHEMBL20863084 | 0.64 | HRH2 (0.47) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL2197651 | 0.61 | KDM1A (0.58) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL2936924 | 0.61 | KDM1A (0.58) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL433970 | 0.61 | GRIN2B (0.69) | ACHEBACE1BCHEGRIN2BKMT2A | |
| SCHEMBL2798417 | 0.61 | KDM1A (0.58) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL2198525 | 0.61 | KDM1A (0.58) | ACHEBACE1BCHEGRIN2BKDM1A | |
| SCHEMBL491107 | 0.61 | KDM1A (0.58) | ACHEBACE1BCHEGRIN2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124647-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| EP-2144505-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008119511-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1977644-A1 | Insecticidal derivatives of substituted benzylamines | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124647-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BCHE, PNMT, TMBIM6 | ACHE 10/4885BACE1 434/4885BCHE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.