Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789526 | 0.72 | ACHE (0.37) | GRIN2BKDM1AMAOAFUCA1IDO1 | |
| SCHEMBL28651661 | 0.72 | NFKB1 (0.34) | IDO1TDP1CYP3A4HSD17B10 | |
| SCHEMBL28473531 | 0.69 | — | — | |
| SCHEMBL27537953 | 0.69 | — | — | |
| SCHEMBL6129603 | 0.68 | GBA1 (0.33) | TDP1SLC6A3HSD17B10 | |
| SCHEMBL20863084 | 0.66 | HRH2 (0.47) | GRIN2BKDM1AMAOAFUCA1IDO1 | |
| SCHEMBL29940611 | 0.64 | GRIN2B (0.42) | GRIN2BKDM1AMAOAFUCA1IDO1 | |
| SCHEMBL21518380 | 0.63 | GRIN2B (0.38) | GRIN2BKDM1AMAOAFUCA1IDO1 | |
| SCHEMBL663239 | 0.62 | GRIN2B (0.74) | GRIN2BMEN1KMT2ABCHEACHE | |
| SCHEMBL25069529 | 0.62 | FUCA1 (0.72) | GRIN2BKDM1AMAOAFUCA1HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200323206-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INTERNATIONAL LTD. (CH) | 2020-10-15 | — | — | US | claimed |
| EP-3468363-B1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INT LTD (CH) | 2020-03-04 | — | — | EP | claimed |
| EP-3468363-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | Clariant International Ltd (CH) | 2019-04-17 | — | — | EP | claimed |
| WO-2017211572-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INTERNATIONAL LTD (CH) | 2017-12-14 | — | — | WO | claimed |
| US-20200323206-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INTERNATIONAL LTD. (CH) | 2020-10-15 | — | — | US | disclosed |
| EP-3468363-B1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INT LTD (CH) | 2020-03-04 | — | — | EP | disclosed |
| EP-3468363-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | Clariant International Ltd (CH) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017211572-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | CLARIANT INTERNATIONAL LTD (CH) | 2017-12-14 | — | — | WO | disclosed |
| WO-2002038769-A2 | DNA SEQUENCES, WHICH CODE FOR OPTIMISED EUKARYOTIC HPV 16-L1 AND HPV 16-L2 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323206-A1 | USE OF N-SUBSTITUTED PYRROLIDONES TO PROMOTE THE PENETRATION OF AGROCHEMICAL ACTIVE AGENTS | HMBS, PAH, HPD | GRIN2B 1690/4885KDM1A 724/4885MAOA 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.