Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17895769 | 0.99 | LMNA (0.31) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17895842 | 0.90 | USP2 (0.43) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17896121 | 0.89 | LMNA (0.34) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17895780 | 0.88 | LMNA (0.34) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17895925 | 0.86 | LMNA (0.33) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17896071 | 0.85 | ALDH1A1 (0.34) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17896017 | 0.85 | LMNA (0.34) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17896063 | 0.85 | TSHR (0.35) | LMNATSHRKDM4EALDH1A1POLB | |
| SCHEMBL17896005 | 0.85 | KDM4E (0.34) | LMNATSHRKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL17896047 | 0.85 | TSHR (0.34) | LMNATSHRKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |