Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17896027 | 0.99 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHRSMN1; SMN2PKM | |
| SCHEMBL17896121 | 0.90 | LMNA (0.34) | KDM4EALDH1A1TSHRSMN1; SMN2PKM | |
| SCHEMBL17895780 | 0.89 | LMNA (0.34) | KDM4EALDH1A1TSHRSMN1; SMN2PKM | |
| SCHEMBL17895925 | 0.87 | LMNA (0.33) | KDM4EALDH1A1TSHRSMN1; SMN2PKM | |
| SCHEMBL17896017 | 0.86 | LMNA (0.34) | KDM4EALDH1A1TSHRPKMLMNA | |
| SCHEMBL17896063 | 0.86 | TSHR (0.35) | KDM4EALDH1A1TSHRSMN1; SMN2PKM | |
| SCHEMBL17896071 | 0.86 | ALDH1A1 (0.34) | KDM4EALDH1A1TSHRPKMLMNA | |
| SCHEMBL17895950 | 0.86 | BRPF1 (0.35) | KDM4EALDH1A1TSHRLMNAUSP2 | |
| Hydrochloric Acid SCHEMBL17895890 | 0.85 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHRPKMLMNA | |
| Hydrochloric Acid SCHEMBL17896047 | 0.85 | TSHR (0.34) | KDM4EALDH1A1TSHRSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |