Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17895974 | 0.99 | ALDH1A1 (0.37) | ALDH1A1RAD52CRHBPCRHR2HIF1A | |
| SCHEMBL17896285 | 0.95 | CRHBP (0.38) | ALDH1A1CRHBPCRHR2HIF1ALMNA | |
| SCHEMBL17896078 | 0.90 | HTT (0.34) | ALDH1A1LMNAKDM4EMAPTALOX12 | |
| Trifluoroacetic Acid SCHEMBL17895773 | 0.90 | CRHBP (0.35) | ALDH1A1CRHBPCRHR2HIF1ATP53 | |
| SCHEMBL17895779 | 0.88 | LMNA (0.34) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL17895829 | 0.88 | MAPT (0.34) | ALDH1A1LMNAKDM4EMAPTL3MBTL1 | |
| SCHEMBL17895899 | 0.87 | LMNA (0.33) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL17896153 | 0.86 | LMNA (0.37) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL17895905 | 0.85 | LMNA (0.34) | ALDH1A1LMNAKDM4EMAPTTSHR | |
| SCHEMBL17895828 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EALOX12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |