Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896001 | 0.95 | ALDH1A1 (0.37) | CRHBPCRHR2HIF1AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL17895773 | 0.95 | CRHBP (0.35) | CRHBPCRHR2HIF1AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL17895974 | 0.94 | ALDH1A1 (0.37) | CRHBPCRHR2HIF1AALDH1A1MAPT | |
| SCHEMBL17895779 | 0.89 | LMNA (0.34) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17895899 | 0.88 | LMNA (0.33) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17896078 | 0.87 | HTT (0.34) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17896153 | 0.87 | LMNA (0.37) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17895905 | 0.86 | LMNA (0.34) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17895829 | 0.85 | MAPT (0.34) | ALDH1A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL17895978 | 0.83 | LMNA (0.34) | ALDH1A1MAPTLMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |