Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 18/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | PDE2A | O00408 | 1/20 | 0.72 |
| ▸ | RGS12 | O14924 | 1/20 | 0.72 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.72 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.72 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.72 |
| ▸ | PDE6D | O43924 | 1/20 | 0.72 |
| ▸ | PDE8A | O60658 | 1/20 | 0.72 |
| ▸ | GMNN | O75496 | 1/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | PDE5A | O76074 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055565 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| SCHEMBL5055315 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| SCHEMBL29973155 | 0.92 | SLC29A1 (0.86) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| Dipyridamole SCHEMBL16119 | 0.85 | SLC29A1 (1.00) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| SCHEMBL30416820 | 0.85 | SLC29A1 (1.00) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| SCHEMBL29541182 | 0.85 | SLC29A1 (0.54) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| Dipyridamole SCHEMBL29381078 | 0.85 | SLC29A1 (1.00) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| Dipyridamole SCHEMBL3980595 | 0.85 | SLC29A1 (1.00) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| Dipyridamole SCHEMBL7998210 | 0.83 | SLC29A1 (0.97) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 | |
| Dipyridamole SCHEMBL9743915 | 0.83 | SLC29A1 (0.97) | SLC29A1ADORA3MEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381197-B2 | Processes for the preparation of dipyridamole | GENERICS [UK] LIMITED (GB) | 2016-07-05 | — | — | US | disclosed |
| US-9381197-B2 | Processes for the preparation of dipyridamole | GENERICS [UK] LIMITED (GB) | 2016-07-05 | — | — | US | disclosed |