SCHEMBL5055315

SCHEMBL5055315

OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N(CCO)CCO)c2n1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 19/20 0.86
▸ ADORA3 P0DMS8 2/20 0.86
▸ KDM4E B2RXH2 1/20 0.86
▸ MEN1 O00255 1/20 0.86
▸ PDE2A O00408 1/20 0.86
▸ RGS12 O14924 1/20 0.86
▸ SLC22A2 O15244 1/20 0.86
▸ SLC22A1 O15245 1/20 0.86
▸ ABCC4 O15439 1/20 0.86
▸ ABCC5 O15440 1/20 0.86
▸ PDE6D O43924 1/20 0.86
▸ PDE8A O60658 1/20 0.86
▸ GMNN O75496 1/20 0.86
▸ USP2 O75604 1/20 0.86
▸ PDE5A O76074 1/20 0.86
▸ ABCB11 O95342 1/20 0.86
▸ ALDH1A1 P00352 1/20 0.86
▸ LMNA P02545 1/20 0.86
▸ HSP90AA1 P07900 1/20 0.86
▸ CHRM2 P08172 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridamole SCHEMBL16119 0.93 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL3980595 0.93 SLC29A1 (1.00) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL17896290 0.92 SLC29A1 (0.72) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL9743915 0.91 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL7362290 0.91 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL7998210 0.91 SLC29A1 (0.97) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL17044166 0.90 SLC29A1 (0.94) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL611283 0.88 SLC29A1 (0.91) SLC29A1ADORA3KDM4EMEN1PDE2A
Dipyridamole SCHEMBL11234613 0.86 SLC29A1 (0.86) SLC29A1ADORA3KDM4EMEN1PDE2A
SCHEMBL17017272 0.86 SLC29A1 (0.86) SLC29A1ADORA3KDM4EMEN1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025013872-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2025-01-16 — — WO claimed
CN-118291517-A Genetic transformation method for young embryo of induction system by using agrobacterium infection 中国农业大学 2024-07-05 — — CN claimed
CN-114740102-A Dipyridamole impurity positioning solution and preparation method and application thereof 广东省药品检验所(广东省药品质量研究所、广东省口岸药品检验所) 2022-07-12 — — CN claimed
CN-112581743-B Infrared remote control cascade circuit 广州朗国电子科技股份有限公司 2022-03-08 — — CN claimed
US-12540144-B2 Rapafucin derivative compounds and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2026-02-03 — — US disclosed
WO-2025013872-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2025-01-16 — — WO disclosed
CN-114740102-B Dipyridamole Mo Zazhi positioning solution and preparation method and application thereof 广东省药品检验所(广东省药品质量研究所、广东省口岸药品检验所) 2024-12-24 — — CN disclosed
US-20240239810-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2024-07-18 — — US disclosed
CN-118291517-A Genetic transformation method for young embryo of induction system by using agrobacterium infection 中国农业大学 2024-07-05 — — CN disclosed
US-11945827-B2 Rapafucin derivative compounds and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2024-04-02 — — US disclosed
US-20230000996-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2023-01-05 — — US disclosed
US-20220363692-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2022-11-17 — — US disclosed
CN-114740102-A Dipyridamole impurity positioning solution and preparation method and application thereof 广东省药品检验所(广东省药品质量研究所、广东省口岸药品检验所) 2022-07-12 — — CN disclosed
CN-114740102-A Dipyridamole impurity positioning solution and preparation method and application thereof 广东省药品检验所(广东省药品质量研究所、广东省口岸药品检验所) 2022-07-12 — — CN disclosed
CN-112581743-B Infrared remote control cascade circuit 广州朗国电子科技股份有限公司 2022-03-08 — — CN disclosed
US-9381197-B2 Processes for the preparation of dipyridamole GENERICS [UK] LIMITED (GB) 2016-07-05 — — US disclosed
US-9381197-B2 Processes for the preparation of dipyridamole GENERICS [UK] LIMITED (GB) 2016-07-05 — — US disclosed
EP-1894561-A1 Dipyridamole pharmaceutical compositions Dr. Reddy's Laboratories Ltd. (IN) 2008-03-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220363692-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF RICTOR, FKBP14, MTOR SLC29A1 3759/4885ADORA3 4468/4885KDM4E 3663/4885
US-20230000996-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF RICTOR, FKBP14, MTOR SLC29A1 3759/4885ADORA3 4468/4885KDM4E 3663/4885
US-11945827-B2 Rapafucin derivative compounds and methods of use thereof RICTOR, FKBP14, MTOR SLC29A1 3759/4885ADORA3 4468/4885KDM4E 3663/4885
US-12540144-B2 Rapafucin derivative compounds and methods of use thereof RICTOR, CHP1, FKBP8 SLC29A1 1736/4885ADORA3 4421/4885KDM4E 4000/4885
US-20240239810-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF RICTOR, MTOR, FKBP14 SLC29A1 3334/4885ADORA3 4498/4885KDM4E 3832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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