Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907592 | 0.83 | CDK2 (0.46) | CDK1XDHHPRT1ADORA2AADORA1 | |
| SCHEMBL25745271 | 0.80 | PI4KA (0.39) | CYP3A4XDHCDK4CCND1HPRT1 | |
| SCHEMBL9910656 | 0.78 | XDH (0.42) | CDK1CYP3A4MAPK1PMP22XDH | |
| SCHEMBL18521149 | 0.77 | CDK1 (0.40) | CDK1CYP3A4MAPK1PMP22XDH | |
| 9-Methylguanine SCHEMBL22884 | 0.77 | XDH (0.58) | XDHHPRT1TK1 | |
| SCHEMBL3427614 | 0.77 | CDK1 (0.47) | CDK1CYP3A4MAPK1PMP22XDH | |
| SCHEMBL26010885 | 0.76 | YTHDC1 (0.42) | YTHDC1TK1GDAPDE4APDE4B | |
| SCHEMBL25768778 | 0.76 | IMPDH2 (0.36) | CYP3A4XDHCDK4CCND1HPRT1 | |
| 9-Methylguanine SCHEMBL27339404 | 0.75 | XDH (0.57) | XDHHPRT1TK1 | |
| SCHEMBL25100647 | 0.74 | CDK1 (0.38) | CDK1CYP3A4MAPK1PMP22XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019023651-A2 | SMALL MOLECULE MODULATORS OF THE ANDROGEN RECEPTOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-31 | — | — | WO | disclosed |
| US-20160193150-A1 | REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160193150-A1 | REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME | PHAX, PCNP, NUP205 | CDK1 3945/4885CYP3A4 4806/4885MAPK1 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.