Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782859 | 0.76 | NPC1 (0.43) | NPC1MAOATDP1KDM4EGPR3 | |
| SCHEMBL17891982 | 0.72 | MAPT (0.38) | NPC1MAOATDP1KDM4EGPR3 | |
| SCHEMBL17891984 | 0.72 | KMT2A (0.40) | NPC1MAOATDP1KDM4EGPR3 | |
| SCHEMBL8882478 | 0.68 | FDPS (0.43) | NPC1TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL21727267 | 0.65 | ALDH1A1 (0.32) | TDP1ALDH1A1HPGDMAPK1LMNA | |
| SCHEMBL21727255 | 0.65 | ALDH1A1 (0.32) | KDM4EALDH1A1MAPT | |
| SCHEMBL27402471 | 0.64 | TDP1 (0.46) | TDP1MAPK1TSHR | |
| SCHEMBL2015417 | 0.64 | HIF1A (0.43) | NPC1MAOATDP1KDM4EALDH1A1 | |
| SCHEMBL13310735 | 0.64 | PIN1 (0.43) | NPC1MAOAKDM4EALDH1A1HPGD | |
| SCHEMBL8789401 | 0.64 | POLB (0.44) | NPC1KDM4EALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107742-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-07 | — | — | WO | disclosed |