SCHEMBL17899354

SCHEMBL17899354

c1cc(-c2cnc3c(ccc4ccc(-c5ccc6oc7ccccc7c6c5)nc43)c2)cc(-c2cnc3c(ccc4ccc(-c5ccc6oc7ccccc7c6c5)nc43)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
PLA2G10 O15496 1/20 0.38
PGR P06401 1/20 0.37
KDM4E B2RXH2 3/20 0.36
CLK2 P49760 2/20 0.35
HIPK1 Q86Z02 2/20 0.35
DYRK2 Q92630 2/20 0.35
HIPK2 Q9H2X6 2/20 0.35
HIPK3 Q9H422 2/20 0.35
CLK4 Q9HAZ1 2/20 0.35
CLK1 P49759 1/20 0.35
DYRK1A Q13627 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
MAPT P10636 3/20 0.35
NPC1 O15118 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15582219 0.89 MAPT (0.42) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581760 0.88 CASP3 (0.41) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581748 0.88 PLA2G2A (0.45) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL19767460 0.88 NPC1 (0.44) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581941 0.87 MAPT (0.40) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581806 0.87 MAPT (0.40) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581800 0.87 CASP3 (0.40) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581792 0.87 PLA2G2A (0.41) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581816 0.87 PLA2G2A (0.44) CASP3SENP7SENP6PLA2G2APLA2G4A
SCHEMBL15581813 0.87 PLA2G2A (0.44) CASP3SENP7SENP6PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2896621-B1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2018-04-25 EP disclosed
US-20180102484-A1 NEW COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-04-12 US disclosed
US-20180102484-A1 NEW COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-04-12 US disclosed
US-9871206-B2 Compound, organic electroluminescence device material, organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-9871206-B2 Compound, organic electroluminescence device material, organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180102484-A1 NEW COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE CBX8, MLX, HAX1 CASP3 4077/4885SENP7 3871/4885SENP6 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.