SCHEMBL17899375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17899369	0.92	SLC6A2 (0.38)	CHEK2PARP10SMN1; SMN2SLC6A2SLC6A4
	SCHEMBL17888545	0.90	KDM4E (0.39)	MAOBSMN1; SMN2KDM4EMAPTADRB2
	SCHEMBL17899371	0.87	ICAM1 (0.41)	CHEK2MAOBPARP10SMN1; SMN2SLC6A2
	SCHEMBL17888615	0.85	PDE4D (0.38)	CHEK2PARP10PARP15PARP2PDE4D
	SCHEMBL17899363	0.83	PARP10 (0.37)	CHEK2PARP10SLC6A2SLC6A4PARP15
	SCHEMBL17888598	0.83	PARP10 (0.38)	CHEK2PARP10SMN1; SMN2KDM4EMAPT
	SCHEMBL17888612	0.83	PDE4D (0.39)	PARP10SLC6A2SLC6A4PARP15PARP2
	SCHEMBL17899127	0.82	CHEK2 (0.38)	CHEK2PARP10PARP15PARP2PDE4D
	SCHEMBL17888597	0.82	PDE4D (0.37)	PARP10SMN1; SMN2PARP15PARP2PDE4D
	SCHEMBL17899128	0.82	PDE4D (0.37)	PARP10SMN1; SMN2PARP15PARP2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.