SCHEMBL17899371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17899375	0.87	CHEK2 (0.39)	MAOBSLC6A2SLC6A4CHEK2PARP10
	SCHEMBL17899370	0.85	PDE4D (0.39)	ICAM1SELEMAOBSCN9AOPRK1
	SCHEMBL17888686	0.85	ICAM1 (0.38)	ICAM1SELEMAOBSCN9ASLC6A2
	SCHEMBL17888567	0.84	OPRK1 (0.39)	ICAM1SELESCN9AOPRK1OPRM1
	SCHEMBL17899402	0.82	KDM4E (0.42)	ICAM1SELEPARP10SMN1; SMN2KDM4E
	SCHEMBL17899369	0.80	SLC6A2 (0.38)	SLC6A2SLC6A4CHEK2OPRK1OPRM1
	SCHEMBL17888545	0.77	KDM4E (0.39)	MAOBSCN9AEPHX2SMN1; SMN2PDE4D
	SCHEMBL17899157	0.74	PDE4D (0.39)	OPRK1OPRM1OPRD1PDE4D
	SCHEMBL17888565	0.73	LIPG (0.39)	MAOBSCN9ASLC6A2SLC6A4CHEK2
	SCHEMBL21697477	0.73	PARP10 (0.54)	ICAM1SELEMAOBSCN9ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.