SCHEMBL17899391

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17899389	0.88	MAPK1 (0.37)	PARP10PARP14MAPTMAPK1PARP15
	SCHEMBL17899151	0.85	ACACB (0.36)	PARP10PARP14MAPTMAPK1SCN9A
	SCHEMBL17899409	0.82	PARP10 (0.39)	PARP10PARP14MAPTPARP15ALDH1A1
	SCHEMBL21697466	0.82	SLC6A4 (0.40)	PARP10PARP14MAPTMAPK1PARP15
	SCHEMBL17899403	0.79	PARP14 (0.37)	PARP10PARP14MAPTPARP1CHEK2
	SCHEMBL17888597	0.72	PDE4D (0.37)	PARP10MAPK1PARP15ALDH1A1PARP2
	SCHEMBL17888594	0.72	PDE4D (0.37)	PARP10MAPK1PARP15ALDH1A1PARP2
	SCHEMBL17899128	0.72	PDE4D (0.37)	PARP10MAPK1PARP15ALDH1A1PARP2
	SCHEMBL21697468	0.71	SLC6A4 (0.39)	PARP10PARP14MAPTMAPK1PARP15
	SCHEMBL17899153	0.70	PARP10 (0.37)	PARP10PARP14MAPTPARP15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.