Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897332 | 0.88 | EPHX2 (0.41) | EPHX2GAAALDH1A1SMN1; SMN2GSTP1 | |
| SCHEMBL17899697 | 0.88 | LMNA (0.43) | EPHX2GAAALDH1A1PKMMAPT | |
| SCHEMBL17899649 | 0.88 | KMT2A (0.41) | EPHX2GAASMN1; SMN2PKMMAPT | |
| SCHEMBL17899639 | 0.88 | PKM (0.43) | EPHX2GAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL17899640 | 0.87 | GAA (0.42) | EPHX2GAAALDH1A1SMN1; SMN2GSTP1 | |
| SCHEMBL17899694 | 0.86 | PKM (0.48) | EPHX2GAAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL17899650 | 0.86 | KMT2A (0.46) | EPHX2GAAALDH1A1MAPTKMT2A | |
| SCHEMBL17899643 | 0.86 | GAA (0.43) | GAAALDH1A1SMN1; SMN2PKMGSTP1 | |
| SCHEMBL17899699 | 0.86 | KMT2A (0.39) | EPHX2GAASMN1; SMN2PKMKMT2A | |
| SCHEMBL17899648 | 0.85 | KMT2A (0.48) | GAAALDH1A1SMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266489-B2 | Pyrrolic amide compound and preparation method and application thereof | HITGEN LTD (CN) | 2019-04-23 | — | — | US | disclosed |
| EP-3241823-B1 | PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | HITGEN LTD (CN) | 2019-04-17 | — | — | EP | disclosed |
| EP-3241823-A1 | PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hitgen Ltd. (CN) | 2017-11-08 | — | — | EP | disclosed |
| US-20170298016-A1 | PYRROLIC AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | HITGEN INC. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170298016-A1 | PYRROLIC AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | HITGEN INC. (CN) | 2017-10-19 | — | — | US | disclosed |
| WO-2016107544-A1 | INTERMEDIATE COMPOUND FOR PREPARING PYRROLE AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 成都先导药物开发有限公司 | 2016-07-07 | — | — | WO | disclosed |
| WO-2016107227-A1 | PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都先导药物开发有限公司 | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298016-A1 | PYRROLIC AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | HDAC1, HDAC3, HDAC11 | EPHX2 2695/4885ALB 3616/4885GAA 1657/4885 |
| US-10266489-B2 | Pyrrolic amide compound and preparation method and application thereof | HDAC1, HDAC3, HDAC11 | EPHX2 2695/4885ALB 3616/4885GAA 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.