Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899699 | 0.97 | KMT2A (0.39) | KMT2APOLBEPHX2KDM4EL3MBTL1 | |
| SCHEMBL17897332 | 0.90 | EPHX2 (0.41) | KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL17899697 | 0.90 | LMNA (0.43) | KMT2AEPHX2KDM4EPKMTDP1 | |
| SCHEMBL17899639 | 0.90 | PKM (0.43) | KMT2AEPHX2SMN1; SMN2PKMGAA | |
| SCHEMBL17899640 | 0.89 | GAA (0.42) | KMT2AEPHX2SMN1; SMN2GAAMEN1 | |
| SCHEMBL17899688 | 0.89 | ALDH1A1 (0.46) | KMT2APOLBSMN1; SMN2PKMGAA | |
| SCHEMBL17899628 | 0.88 | EPHX2 (0.44) | KMT2AEPHX2SMN1; SMN2PKMGAA | |
| SCHEMBL17899650 | 0.88 | KMT2A (0.46) | KMT2AEPHX2GAAMEN1MAPT | |
| SCHEMBL17899694 | 0.88 | PKM (0.48) | KMT2APOLBEPHX2KDM4ESMN1; SMN2 | |
| SCHEMBL17899645 | 0.88 | ATR (0.37) | KMT2AKDM4EL3MBTL1PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107544-A1 | INTERMEDIATE COMPOUND FOR PREPARING PYRROLE AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 成都先导药物开发有限公司 | 2016-07-07 | — | — | WO | disclosed |