Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899640 | 0.90 | GAA (0.42) | GAAALDH1A1KMT2AMAPK1GSTP1 | |
| SCHEMBL17899650 | 0.90 | KMT2A (0.46) | GAAALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL17899697 | 0.89 | LMNA (0.43) | GAAALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL17899694 | 0.88 | PKM (0.48) | GAAALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL17897332 | 0.87 | EPHX2 (0.41) | GAAALDH1A1KMT2AMAPK1GSTP1 | |
| SCHEMBL17899649 | 0.87 | KMT2A (0.41) | GAAKMT2ASMN1; SMN2MEN1PKM | |
| SCHEMBL17899639 | 0.87 | PKM (0.43) | GAAALDH1A1KMT2AGSTP1GSTM2 | |
| SCHEMBL17899665 | 0.87 | KMT2A (0.44) | GAAALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL17899648 | 0.86 | KMT2A (0.48) | GAAALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL17899628 | 0.86 | EPHX2 (0.44) | GAAALDH1A1KMT2AMAPK1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016107544-A1 | INTERMEDIATE COMPOUND FOR PREPARING PYRROLE AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 成都先导药物开发有限公司 | 2016-07-07 | — | — | WO | disclosed |