Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443869 | 1.00 | CTSK (0.31) | CTSKCNR2ROCK2 | |
| SCHEMBL16348703 | 0.73 | PKM (0.34) | ROCK2 | |
| SCHEMBL10773183 | 0.73 | CYP1A2 (0.39) | CTSK | |
| SCHEMBL17900527 | 0.72 | PSEN1 (0.35) | CTSK | |
| SCHEMBL14148643 | 0.70 | CSNK1E (0.38) | CNR2 | |
| SCHEMBL6568659 | 0.70 | POLB (0.39) | CTSKCNR2 | |
| SCHEMBL17750751 | 0.70 | POLB (0.39) | CTSKCNR2 | |
| SCHEMBL16199147 | 0.70 | POLB (0.39) | CTSKCNR2 | |
| SCHEMBL14434711 | 0.68 | CSNK1E (0.39) | CNR2 | |
| Hydrochloric Acid SCHEMBL19809583 | 0.68 | POLB (0.38) | CTSKCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194331-A1 | METHOD FOR PRODUCING SPIROOXINDOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194331-A1 | METHOD FOR PRODUCING SPIROOXINDOLE DERIVATIVE | MDM2, TP53, RB1 | CTSK 2697/4885CNR2 4281/4885ROCK2 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.