Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17900715 | 0.94 | AAK1 (0.41) | MEN1THRBKMT2AAAK1KDM4E | |
| SCHEMBL17900546 | 0.91 | KDM4E (0.45) | MEN1THRBKMT2AAAK1KDM4E | |
| SCHEMBL17900710 | 0.87 | KDM4E (0.39) | MEN1THRBKMT2AAAK1KDM4E | |
| SCHEMBL17900615 | 0.84 | NR3C1 (0.41) | MEN1THRBKMT2AKDM4EHPGD | |
| SCHEMBL17900711 | 0.84 | ALDH1A1 (0.42) | MEN1THRBKMT2AAAK1KDM4E | |
| SCHEMBL17905643 | 0.82 | AAK1 (0.42) | MEN1THRBKMT2AAAK1KDM4E | |
| SCHEMBL17900541 | 0.82 | KDM4E (0.42) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL17900638 | 0.82 | KDM4E (0.42) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL17900707 | 0.82 | KDM4E (0.45) | MEN1KMT2AAAK1KDM4EHPGD | |
| SCHEMBL17900537 | 0.82 | KDM4E (0.45) | MEN1KMT2AAAK1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| WO-2016109305-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109304-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | MEN1 2009/4885THRB 3204/4885KMT2A 2803/4885 |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | PFAS, CYP1A2, CYP4F12 | MEN1 2756/4885THRB 3631/4885KMT2A 3348/4885 |
| US-10173981-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | MEN1 2009/4885THRB 3204/4885KMT2A 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.