Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.72 |
| ▸ | MAOA | P21397 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA3 | P07451 | 2/20 | 0.68 |
| ▸ | CA6 | P23280 | 2/20 | 0.68 |
| ▸ | CA5A | P35218 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.68 |
| ▸ | MIF | P14174 | 2/20 | 0.57 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103400 | 0.88 | MIF (0.72) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL18589240 | 0.85 | MAOB (0.70) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL29985431 | 0.85 | KDM4E (0.68) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL6417829 | 0.84 | MAOB (1.00) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL1808756 | 0.84 | MAOA (0.71) | MAOAKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL22502678 | 0.84 | MEN1 (0.72) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL10651297 | 0.84 | KDM4E (0.67) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL6835643 | 0.84 | KDM4E (0.76) | MAOBKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL18752472 | 0.82 | CA12 (0.82) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL29575367 | 0.82 | CA12 (0.65) | MAOBMAOAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109733-A1 | HIGHLY SENSITIVE DETECTION OF BIOMOLECULES USING PROXIMITY INDUCED BIOORTHOGONAL REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-07-07 | — | — | WO | disclosed |