Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905434 | 0.92 | NPC1 (0.34) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17905239 | 0.90 | IDO1 (0.34) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL17905193 | 0.90 | MAPT (0.35) | SMN1; SMN2NPC1RAB9ATP53MAPT | |
| SCHEMBL17896230 | 0.89 | HTT (0.35) | MEN1KMT2AALDH1A1HPGDMAPK1 | |
| SCHEMBL17905159 | 0.89 | HTT (0.35) | MEN1KMT2AALDH1A1HPGDMAPK1 | |
| SCHEMBL17905461 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17905691 | 0.86 | HTT (0.36) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL17904921 | 0.86 | LMNA (0.36) | SMN1; SMN2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL17905136 | 0.85 | NPC1 (0.35) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17905696 | 0.85 | GRM4 (0.33) | SMN1; SMN2ALDH1A1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SMN1; SMN2 2463/4885MEN1 2200/4885KMT2A 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.