Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905159 | 1.00 | HTT (0.35) | HTTGRM5ALDH1A1KMT2AHPGD | |
| SCHEMBL17905691 | 0.97 | HTT (0.36) | HTTGRM5ALDH1A1KMT2AHPGD | |
| SCHEMBL17896210 | 0.92 | HTT (0.36) | HTTGRM5ALDH1A1KMT2AHPGD | |
| SCHEMBL17904981 | 0.92 | HTT (0.36) | HTTGRM5ALDH1A1KMT2AHPGD | |
| SCHEMBL17905193 | 0.92 | MAPT (0.35) | HTTHPGDMAPK1POLB | |
| SCHEMBL17905181 | 0.91 | HCRTR1 (0.33) | ALDH1A1KMT2AMEN1MAPK1POLB | |
| SCHEMBL17905134 | 0.91 | ALDH1A1 (0.33) | ALDH1A1KMT2AHPGDMEN1MAPK1 | |
| SCHEMBL17905198 | 0.90 | MTNR1A (0.36) | HTTALDH1A1POLB | |
| SCHEMBL17904894 | 0.89 | SMN1; SMN2 (0.34) | ALDH1A1KMT2AHPGDMEN1MAPK1 | |
| SCHEMBL17896206 | 0.89 | HTT (0.37) | HTTGRM5ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000075-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| EP-3240412-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240413-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000075-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | HTT 3579/4885GRM5 1463/4885ALDH1A1 1350/4885 |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | HTT 3579/4885GRM5 1463/4885ALDH1A1 1350/4885 |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CYP1A2, CYP51A1 | HTT 3790/4885GRM5 1422/4885ALDH1A1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.