Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17904858 | 0.99 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17905551 | 0.96 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL20682906 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17901156 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17901158 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17901266 | 0.94 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17901254 | 0.94 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL20682896 | 0.94 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPK1NPSR1 | |
| SCHEMBL17905632 | 0.92 | KMT2A (0.38) | ALDH1A1MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL17904775 | 0.91 | NR3C1 (0.34) | ALDH1A1MEN1KMT2ANPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | ALDH1A1 1350/4885MEN1 2200/4885KMT2A 3102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.