Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266911 | 0.98 | RAB9A (0.45) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29374931 | 0.79 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL170196 | 0.79 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30883993 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31243061 | 0.77 | ALDH1A1 (0.63) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10866984 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28990083 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL34463709 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31490600 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31365172 | 0.77 | RAB9A (0.61) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017244-B | Process for preparing triazolyl quinoline derivatives | ALKALOIDA WEGYESZETI GYAR (HU) | 1992-07-01 | — | — | CN | claimed |
| US-5104884-A | Rheumatic diseases, fungicides | ALKALOIDA VEGYESZETI GYAR (HU) | 1992-04-14 | — | — | US | claimed |
| EP-0221947-B1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1990-11-28 | — | — | EP | claimed |
| CN-86103997-A | The preparation method of triazolyl quinoline derivative class | — | 1987-12-30 | — | — | CN | claimed |
| EP-0221947-A1 | TRIAZOLYL QUINOLINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-05-20 | — | — | EP | claimed |
| WO-1986006721-A1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1986-11-20 | — | — | WO | claimed |
| EP-4463230-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | Debreceni Egyetem (HU) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023041947-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2023-03-23 | — | — | WO | disclosed |
| US-20210107896-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | UNIV YALE (US) | 2021-04-15 | — | — | US | disclosed |
| US-10899739-B2 | Macrophage migration inhibitory factor inhibitors, and methods of making and using same | YALE UNIVERSITY (US) | 2021-01-26 | — | — | US | disclosed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |
| US-20190144424-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | YALE UNIVERSITY | 2019-05-16 | — | — | US | disclosed |
| CN-109206405-A | Triazolyl quinoline copper complex with AIE property and preparation method thereof | 阜阳师范学院 | 2019-01-15 | — | — | CN | disclosed |
| EP-0221947-B1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1990-11-28 | — | — | EP | disclosed |
| CN-86103997-A | The preparation method of triazolyl quinoline derivative class | — | 1987-12-30 | — | — | CN | disclosed |
| CN-86103997-A | The preparation method of triazolyl quinoline derivative class | — | 1987-12-30 | — | — | CN | disclosed |
| EP-0221947-A1 | TRIAZOLYL QUINOLINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-05-20 | — | — | EP | disclosed |
| EP-0221947-A1 | TRIAZOLYL QUINOLINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-05-20 | — | — | EP | disclosed |
| WO-1986006721-A1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1986-11-20 | — | — | WO | disclosed |
| WO-1986006721-A1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1986-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107896-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | RAB9A 4213/4885NPC1 4328/4885ALDH1A1 2061/4885 |
| US-20190144424-A1 | Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same | MIF, MMP12, METAP1 | RAB9A 4213/4885NPC1 4328/4885ALDH1A1 2061/4885 |
| US-10899739-B2 | Macrophage migration inhibitory factor inhibitors, and methods of making and using same | MIF, MMP12, METAP1 | RAB9A 4213/4885NPC1 4328/4885ALDH1A1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.