Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913091 | 0.89 | TDP1 (0.67) | ALOX12LMNANPSR1GAAALDH1A1 | |
| SCHEMBL17913099 | 0.84 | CA12 (0.56) | NPSR1ALDH1A1KMT2AMEN1LIMK1 | |
| SCHEMBL17913041 | 0.83 | ALDH1A1 (0.57) | ALOX12LMNANPSR1GAAALDH1A1 | |
| SCHEMBL17913062 | 0.81 | TDP1 (0.69) | ALOX12LMNANPSR1GAAALDH1A1 | |
| SCHEMBL17913038 | 0.77 | FAAH (0.55) | ALOX12LMNAGAAALDH1A1KMT2A | |
| SCHEMBL17913039 | 0.77 | MEN1 (0.56) | ALOX12LMNAGAAALDH1A1KMT2A | |
| SCHEMBL17913044 | 0.76 | LIMK2 (0.58) | LMNAGAAALDH1A1KMT2ATDP1 | |
| SCHEMBL17913070 | 0.76 | PPIA (0.59) | ALOX12LMNAGAAALDH1A1KMT2A | |
| SCHEMBL17913097 | 0.76 | PPIA (0.59) | ALOX12LMNAGAAALDH1A1KMT2A | |
| SCHEMBL17913045 | 0.76 | LIMK2 (0.58) | LMNAGAAALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | claimed |