Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913041 | 0.93 | ALDH1A1 (0.57) | MEN1KMT2ALMNAFAAHMGLL | |
| SCHEMBL17913038 | 0.89 | FAAH (0.55) | MEN1KMT2ALMNAFAAHMGLL | |
| SCHEMBL17913070 | 0.87 | PPIA (0.59) | MEN1KMT2APPIALMNAALDH1A1 | |
| SCHEMBL17913095 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2ALMNAFAAHMGLL | |
| SCHEMBL17913097 | 0.87 | PPIA (0.59) | MEN1KMT2APPIALMNAALDH1A1 | |
| SCHEMBL17913056 | 0.84 | LMNA (0.62) | MEN1KMT2ALMNAALDH1A1TDP1 | |
| SCHEMBL25132396 | 0.83 | ALDH1A1 (0.74) | MEN1KMT2APPIALMNAALDH1A1 | |
| SCHEMBL15840711 | 0.83 | ALDH1A1 (0.74) | MEN1KMT2APPIALMNAALDH1A1 | |
| SCHEMBL17913088 | 0.82 | PPIA (0.64) | MEN1KMT2APPIALMNAALDH1A1 | |
| SCHEMBL17066584 | 0.80 | GPR55 (0.80) | MEN1KMT2ALMNAALDH1A1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | claimed |