SCHEMBL16479735

SCHEMBL16479735

C=N/C=N\c1ccccc1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.52
MAPT P10636 6/20 0.43
LMNA P02545 6/20 0.43
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 3/20 0.43
RECQL P46063 2/20 0.43
HPGD P15428 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 1/20 0.43
MPI P34949 1/20 0.43
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
PKM P14618 1/20 0.40
TSHR P16473 3/20 0.38
ACHE P22303 1/20 0.38
HTT P42858 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7591613 0.77 CYP2C9 (0.55) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL239326 0.77 CYP2C9 (0.59) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL239325 0.77 CYP2C9 (0.59) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL29472028 0.77 CYP2C9 (0.59) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL22617845 0.76 ATM (0.38) CYP2C9MAPTALDH1A1KDM4ERECQL
SCHEMBL9336284 0.75 CYP2C9 (0.57) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL12459466 0.75 CYP2C9 (0.57) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL22539007 0.75 CYP2C9 (0.57) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL12332461 0.74 CYP2C9 (0.52) CYP2C9MAPTLMNAALDH1A1KDM4E
SCHEMBL6451652 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242556-A1 NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND SFC CO., LTD. (KR) 2023-08-03 US disclosed
US-20230140397-A1 ANTI-PSMA ANTIBODY-EXATECAN ANALOGUE CONJUGATE AND MEDICAL USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2023-05-04 US disclosed
WO-2022135555-A1 PURINONE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF 江苏恒瑞医药股份有限公司 2022-06-30 WO disclosed
EP-3017488-B1 OPTOELECTRONIC DEVICE AND METHOD FOR PRODUCING AN OPTOELECTRONIC DEVICE OSRAM OLED GMBH (DE) 2020-08-19 EP disclosed
US-10647695-B2 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC (US) 2020-05-12 US disclosed
US-10251880-B2 Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions SATIOGEN PHARMACEUTICALS, INC. (US) 2019-04-09 US disclosed
US-20190038611-A1 Novel CYP34A-Specific Inhibitors and Methods of Using Same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-02-07 US disclosed
US-10166214-B2 Somatostatin receptor subtype 4 (SSTR4) agonists CENTREXION THERAPEUTICS CORPORATION (US) 2019-01-01 US disclosed
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-20180092880-A1 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS ANKURA TRUST COMPANY, LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2018-04-05 US disclosed
US-9868108-B2 Specific sorbent for binding proteins and peptides, and separation method using the same INSTRACTION GMBH (DE) 2018-01-16 US disclosed
EP-2997021-B1 NEW SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS CENTREXION THERAPEUTICS CORP (US) 2017-12-20 EP disclosed
US-20170106349-A1 SPECIFIC SORBENT FOR BINDING PROTEINS AND PEPTIDES, AND SEPARATION METHOD USING THE SAME INSTRACTION GMBH (DE) 2017-04-20 US disclosed
US-9234056-B2 Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body ZEON CORPORATION (JP) 2016-01-12 US disclosed
US-9207362-B2 Copolymer, optically anisotropic substance, and oriented polymer film ZEON CORPORATION (JP) 2015-12-08 US disclosed
EP-2910579-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC SUBSTANCE Zeon Corporation (JP) 2015-08-26 EP disclosed
EP-2910986-A1 RETARDER, CIRCULARLY POLARISING PLATE, AND IMAGE DISPLAY DEVICE Zeon Corporation (JP) 2015-08-26 EP disclosed
US-20150232625-A1 COPOLYMER, OPTICALLY ANISOTROPIC SUBSTANCE, AND ORIENTED POLYMER FILM ZEON CORPORATION (JP) 2015-08-20 US disclosed
EP-2871192-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND Zeon Corporation (JP) 2015-05-13 EP disclosed
US-20140107247-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY ZEON CORPORATION (JP) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10251880-B2 Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions SLC10A2, GPR119, GPBAR1 CYP2C9 3391/4885MAPT 2862/4885LMNA 4867/4885
US-10647695-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 CYP2C9 446/4885MAPT 694/4885LMNA 419/4885
US-20180092880-A1 SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS SSTR4, SSTR3, SSTR1 CYP2C9 3140/4885MAPT 4338/4885LMNA 4510/4885
US-20230140397-A1 ANTI-PSMA ANTIBODY-EXATECAN ANALOGUE CONJUGATE AND MEDICAL USE THEREOF FOLH1, ENPEP, PEPD CYP2C9 1766/4885MAPT 861/4885LMNA 1080/4885
US-20230242556-A1 NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND BCL6B, BRD7, DBF4 CYP2C9 2068/4885MAPT 1321/4885LMNA 1747/4885
US-20190038611-A1 Novel CYP34A-Specific Inhibitors and Methods of Using Same CYP3A43, CYP3A4, CYP4B1 CYP2C9 27/4885MAPT 3916/4885LMNA 4628/4885
US-20140107247-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, AND OPTICALLY ANISOTROPIC BODY H1-0, H1-2, H1-4 CYP2C9 1192/4885MAPT 320/4885LMNA 231/4885
US-10166214-B2 Somatostatin receptor subtype 4 (SSTR4) agonists SSTR4, SSTR3, SSTR1 CYP2C9 3140/4885MAPT 4338/4885LMNA 4510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.