Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512631 | 0.90 | RXFP1 (0.48) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921134 | 0.87 | POLB (0.43) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921128 | 0.84 | NPC1 (0.41) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921133 | 0.84 | HDAC1 (0.52) | GAAKDM4EESR1KMT2AALDH1A1 | |
| SCHEMBL17921141 | 0.83 | HDAC1 (0.51) | GAAKDM4EESR1KMT2AALDH1A1 | |
| SCHEMBL16511766 | 0.78 | NAMPT (0.44) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921137 | 0.77 | GAA (0.49) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921161 | 0.76 | LMNA (0.33) | RXFP1KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL16511786 | 0.76 | HDAC1 (0.56) | RXFP1GAANPSR1KDM4EESR1 | |
| SCHEMBL17921183 | 0.75 | LMNA (0.35) | RXFP1KDM4EALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | DUKE UNIVERSITY | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | Q6ZSR9, MRPL21, XDH | RXFP1 47/4885GAA 587/4885NPSR1 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.