Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921161 | 0.99 | LMNA (0.33) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL17921142 | 0.95 | L3MBTL1 (0.33) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL16511775 | 0.88 | MMP9 (0.38) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL16512858 | 0.87 | MMP9 (0.36) | LMNARXFP1HPGDPOLBL3MBTL1 | |
| SCHEMBL17921182 | 0.87 | ALDH1A1 (0.36) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL17921155 | 0.85 | ALDH1A1 (0.34) | LMNAALDH1A1PRNPRECQLRXFP1 | |
| SCHEMBL17921184 | 0.84 | ALDH1A1 (0.45) | LMNAALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL17921179 | 0.84 | S1PR2 (0.34) | ALDH1A1 | |
| SCHEMBL16511318 | 0.83 | MMP9 (0.36) | LMNARXFP1POLBL3MBTL1KDM4E | |
| SCHEMBL17921187 | 0.83 | DPP4 (0.45) | LMNAALDH1A1HPGDPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | DUKE UNIVERSITY | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | Q6ZSR9, MRPL21, XDH | LMNA 3247/4885ALDH1A1 2944/4885PRNP 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.