Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811578 | 0.82 | ALDH1A1 (0.59) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL21263 | 0.82 | ALDH1A1 (0.69) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL17922583 | 0.82 | ALDH1A1 (0.69) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL1816933 | 0.79 | ALDH1A1 (0.65) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL28298270 | 0.79 | ALDH1A1 (0.65) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL17922587 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1CYP3A4CA12 | |
| SCHEMBL12231 | 0.73 | ALDH1A1 (0.48) | ALDH1A1AHRCYP1A1CYP1B1CYP3A4 | |
| SCHEMBL8312905 | 0.73 | ALDH1A1 (0.42) | ALDH1A1AHRCYP3A4EGFRFFAR4 | |
| SCHEMBL17552680 | 0.73 | — | — | |
| SCHEMBL1477524 | 0.71 | ALDH1A1 (0.46) | ALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200639-A1 | INTERMOLECULAR C-H SILYLATION OF UNACTIVATED ARENES | CCNH, CTTN, CCRL2 | ALDH1A1 3641/4885AHR 122/4885CYP1A1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.