Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605076 | 0.85 | ABCB1 (0.39) | HPGDGABRA1GABRB2HSP90AA1ABCB1 | |
| SCHEMBL28313775 | 0.80 | CA1 (0.45) | HPGDGABRA1GABRB2HSP90AA1ABCB1 | |
| SCHEMBL17930300 | 0.77 | ROCK2 (0.32) | PTPN5 | |
| SCHEMBL17930299 | 0.76 | PTPN5 (0.31) | PTPN5 | |
| SCHEMBL4920369 | 0.76 | GABRA1 (0.47) | HPGDALDH1A1BCL2L1HSD17B10GABRA1 | |
| SCHEMBL31545892 | 0.76 | ABCB1 (0.49) | HPGDGABRA1GABRB2HSP90AA1ABCB1 | |
| SCHEMBL30731374 | 0.75 | LMNA (0.43) | ALDH1A1GABRA1GABRB2CYP1A2AHR | |
| SCHEMBL7715672 | 0.75 | GABRA1 (0.50) | HPGDALDH1A1BCL2L1HSD17B10GABRA1 | |
| SCHEMBL11327097 | 0.75 | HSP90AA1 (0.39) | GABRA1GABRB2HSP90AA1ABCB1AHR | |
| SCHEMBL29073846 | 0.74 | PTGS2 (0.41) | GCGRPTPN5BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-05 | — | — | US | disclosed |
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-21 | — | — | US | disclosed |
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207034-A1 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | HPGD 3969/4885ALDH1A1 3157/4885BCL2L1 1636/4885 |
| US-20170282170-A9 | PHOSPHORUS-CONTAINING CATALYSTS | AR, NR2C2, ORC3 | HPGD 3969/4885ALDH1A1 3157/4885BCL2L1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.