Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561852 | 0.86 | GRM8 (0.42) | GRM8GRM4PTPRC | |
| SCHEMBL17933366 | 0.83 | FDPS (0.35) | FDPS | |
| SCHEMBL17933351 | 0.74 | PTPRC (0.33) | PTPRC | |
| SCHEMBL17933342 | 0.73 | PTPRC (0.30) | PTPRC | |
| SCHEMBL17933339 | 0.72 | PTPRC (0.31) | PTPRC | |
| SCHEMBL17933346 | 0.70 | SCN10A (0.34) | GRM8GRM4FDPSPTPRC | |
| SCHEMBL17933371 | 0.69 | GRM8 (0.30) | GRM8GRM4 | |
| SCHEMBL17933334 | 0.69 | FDPS (0.36) | FDPSPTPRC | |
| SCHEMBL17933350 | 0.69 | GRM8 (0.30) | GRM8GRM4 | |
| SCHEMBL17933356 | 0.69 | FBP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | GRM8 4398/4885GRM4 3973/4885FDPS 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.