SCHEMBL17938403

SCHEMBL17938403

N#CC=Cc1ccc2[nH]c3ccccc3c2c1.NP(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 5/20 0.50
▸ AHR P35869 1/20 0.41
▸ GABRP O00591 1/20 0.40
▸ GABRD O14764 1/20 0.40
▸ GABRA1 P14867 1/20 0.40
▸ GABRB1 P18505 1/20 0.40
▸ GABRG2 P18507 1/20 0.40
▸ GABRB3 P28472 1/20 0.40
▸ GABRA5 P31644 1/20 0.40
▸ GABRA3 P34903 1/20 0.40
▸ GABRA2 P47869 1/20 0.40
▸ GABRB2 P47870 1/20 0.40
▸ GABRA4 P48169 1/20 0.40
▸ GABRE P78334 1/20 0.40
▸ GABRA6 Q16445 1/20 0.40
▸ GABRG1 Q8N1C3 1/20 0.40
▸ GABRG3 Q99928 1/20 0.40
▸ GABRQ Q9UN88 1/20 0.40
▸ KDM4E B2RXH2 3/20 0.39
▸ KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30196749 1.00 KIF11 (0.50) KIF11AHRGABRPGABRDGABRA1
SCHEMBL1276474 0.92 KIF11 (0.58) KIF11AHRGABRPGABRDGABRA1
SCHEMBL29939054 0.92 KIF11 (0.58) KIF11AHRGABRPGABRDGABRA1
SCHEMBL12408493 0.92 KIF11 (0.58) KIF11AHRGABRPGABRDGABRA1
Phosphine SCHEMBL28966245 0.90 KIF11 (0.57) KIF11AHRGABRPGABRDGABRA1
SCHEMBL27033667 0.76 KIF11 (0.40) KIF11GABRPGABRDGABRA1GABRB1
Carbazole SCHEMBL7146435 0.73 ALDH1A1 (0.70) KIF11AHRGABRPGABRDGABRA1
SCHEMBL8079075 0.73 KIF11 (0.66) KIF11AHRGABRPGABRDGABRA1
SCHEMBL28217117 0.73 KIF11 (0.66) KIF11AHRKDM4EKMT2AALDH1A1
SCHEMBL8082181 0.71 KIF11 (0.64) KIF11AHRGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054432-A1 SYSTEMS AND METHODS FOR DNA READING Catalog Technologies, Inc. (US) 2025-03-13 — — WO disclosed
US-20240391945-A1 NUCLEIC ACID SYNTHESIS METHOD USING SEGMENT-TYPE AMIDITE NITTO DENKO CORPORATION (JP) 2024-11-28 — — US disclosed
EP-4089099-A1 NUCLEIC ACID SYNTHESIS METHOD USING SEGMENT-TYPE AMIDITE Nitto Denko Corporation (JP) 2022-11-16 — — EP disclosed
US-20220002790-A1 NUCLEIC ACID-BASED BARCODING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-01-06 — — US disclosed
EP-3874058-A2 NUCLEIC ACID-BASED BARCODING President And Fellows Of Harvard College (US) 2021-09-08 — — EP disclosed
WO-2021141072-A1 NUCLEIC ACID SYNTHESIS METHOD USING SEGMENT-TYPE AMIDITE 日東電工株式会社 2021-07-15 — — WO disclosed
WO-2020131233-A9 NUCLEIC ACID-BASED BARCODING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-08-13 — — WO disclosed
WO-2020131233-A2 NUCLEIC ACID-BASED BARCODING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2020-06-25 — — WO disclosed
US-10513535-B2 Self-replication of nucleic acid origami tiles NEW YORK UNIVERSITY (US) 2019-12-24 — — US disclosed
US-20160215317-A1 SELF-REPLICATION OF NUCLEIC ACID ORIGAMI TILES NEW YORK UNIVERSITY 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391945-A1 NUCLEIC ACID SYNTHESIS METHOD USING SEGMENT-TYPE AMIDITE RNGTT, NSUN2, ATIC KIF11 2442/4885AHR 3047/4885GABRP 3738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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