Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FHIT | P49789 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942933 | 0.84 | KDM4E (0.62) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL12038303 | 0.78 | MAOB (0.40) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL17942938 | 0.74 | ALDH1A1 (0.35) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL17942935 | 0.71 | HSD17B3 (0.56) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL1390620 | 0.69 | LMNA (0.43) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL22274920 | 0.69 | NPC1 (0.69) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL16723484 | 0.68 | GPR35 (0.41) | ALDH1A1HSD17B3MAOBFHITCA12 | |
| SCHEMBL25696572 | 0.68 | MAOB (0.58) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL17942941 | 0.68 | MAPT (0.35) | MAPTHSD17B3MAOB | |
| SCHEMBL4769996 | 0.67 | KDM4E (0.67) | KDM4EGLAGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |