Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | GLA | P06280 | 8/20 | 0.62 |
| ▸ | GAA | P10253 | 7/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | CASP1 | P29466 | 5/20 | 0.58 |
| ▸ | CASP7 | P55210 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAPDH | P04406 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942932 | 0.84 | KDM4E (0.45) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL17942935 | 0.78 | HSD17B3 (0.56) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL4769996 | 0.76 | KDM4E (0.67) | KDM4EGLAGAAALDH1A1HSD17B10 | |
| SCHEMBL17942936 | 0.75 | KDM4E (0.42) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL14930132 | 0.74 | KDM4E (0.64) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL12038288 | 0.73 | KDM4E (0.49) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL4711880 | 0.73 | KDM4E (0.95) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL15842923 | 0.72 | HSD17B3 (0.60) | ALDH1A1HSD17B10HPGDALOX15CA12 | |
| SCHEMBL28374261 | 0.72 | MCL1 (0.55) | KDM4EGLAGAAGFERALDH1A1 | |
| SCHEMBL13110582 | 0.71 | GAPDH (0.46) | KDM4EGLAGAAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |