Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039317 | 0.93 | KMT2A (0.45) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038303 | 0.88 | MAOB (0.40) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038321 | 0.86 | GAPDH (0.39) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL13494166 | 0.85 | GPR35 (0.41) | KDM4EKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL17942948 | 0.81 | RAB9A (0.50) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038319 | 0.78 | KDM4E (0.54) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038323 | 0.78 | MAOB (0.38) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038427 | 0.77 | KDM4E (0.39) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL12038347 | 0.76 | GLA (0.38) | KDM4EKMT2AGLAGAAMEN1 | |
| SCHEMBL31114267 | 0.75 | GPR35 (0.44) | KDM4EKMT2AMEN1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2021-11-16 | — | — | US | disclosed |
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |
| US-8318953-B2 | Reactive coumarin derivatives and their use in cellular analyses | AAT BIOQUEST, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318953-B2 | Reactive coumarin derivatives and their use in cellular analyses | AAT BIOQUEST, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-20110318772-A1 | REACTIVE COUMARIN DERIVATIVES AND THEIR USE IN CELLULAR ANALYSES | AAT BIOQUEST, INC. (US) | 2011-12-29 | — | — | US | disclosed |
| US-20110318772-A1 | REACTIVE COUMARIN DERIVATIVES AND THEIR USE IN CELLULAR ANALYSES | AAT BIOQUEST, INC. (US) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318772-A1 | REACTIVE COUMARIN DERIVATIVES AND THEIR USE IN CELLULAR ANALYSES | CYP3A7, XPO7, HCCS | KDM4E 4529/4885KMT2A 4772/4885GLA 649/4885 |
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | MKI67, DCX, CDK7 | KDM4E 2525/4885KMT2A 2386/4885GLA 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.